As others have pointed out, putting a lot of harvest pressure on does quickly drives them nocturnal. I swear does are smarter than bucks, and respond faster and more efficiently to harvest pressure than bucks do.
That said, you have hundreds of cameras out and you're not getting many does on camera. To me, that suggests does aren't there. So does either left the property (extremely unlikely on a property that large) or they no longer exist in the numbers they used to. I would need to know a lot more about census data from the property as well as harvest numbers over time to make an educated assessment the population dynamics. However, I will make a comment concerning doe harvests that not only applies to your situation but to everyone, and that is watch your fawn recruitment numbers closely. So much of doe harvest policies and strategies promoted by myself and others were based on how deer herds had always operated in the past, with very high fawn production/recruitment that could easily replace harvested adults. It used to be common for local deer populations to have fawn recruitment rates of 100 to 120% (10 to 12 surviving fawns per 10 adult does). In that situation, you can literally shoot 1/3 of the entire adult population year after year and have those harvests completely replaced by the huge fawn crops joining the adult population on their first birthdays.
Yet things have changed in the Southeast and no one really knows why. Across the region fawn recruitment rates have been falling, and in many areas quite dramatically. Now fawn recruitment rates of only 30-40% are being reported all across the region. That's basically what I'm seeing on the properties I census in western Middle TN. Many blame coyotes for the major decline. I agree coyotes are having an impact, but honestly we had very high coyote populations back when recruitment rates used to run 100-120%. I personally believe other factors are exacerbating the coyote predation problem, although I'm clueless as to what those other factors are. But whatever they are, they are regionwide.
No matter the cause, low fawn recruitment has MAJOR implications for harvest strategies. Mathematically speaking, you cannot shoot more adult deer than fawns produced each year without the population declining. As an oversimplified example, imagine a given area has 100 adult does with a 100% fawn recruitment, meaning those 100 does produce 100 surviving fawns. That means close to 100 adult deer can be removed from that population and they will all be replaced by those 100 fawns joining the adult population the following year. But what if fawn recruitment drops to only 50%? Now those 100 adult does are producing only 50 fawns, hence only 50 adult deer can be harvested without the adult population being lower the following year. And what happens when the adult doe population has been reduced through hunter harvest or other forms of mortality, such as CWD/EHD? Let's say the adult doe population drops to 60. Those 60 adult does with a 50% fawn recruitment only produce 30 surviving fawns, which means hunters can only take 30 adult deer without the population declining. So we've gone from being able to kill 100 adult deer to only 30. See how low fawn recruitment can cause a domino effect over time?
Again, I don't know your property's situation or data. But low fawn recruitment, in combination with high mortality rates from hunter harvest, predation and disease can be a real problem. It can really change the dynamics of how the deer population has to be managed.