For me, this is a hard question to answer as there's a lot of variables that play in to how I hunt an area. Variables like what your goals are, buck/doe, size of parcel able to hunt, trails, terrain, etc. Don't get me wrong, I'm certainly no expert, but I can tell you how I would approach the situation. I suspect there will be some pretty good advice offered through this thread.
Generally speaking, I would look for the "main" source of travel to the tree. I know you said they come from all areas, but I would look for what appears to be the 'most' use approach of the deer and hunt down-wind. To be completely honest, I don't know that I would hunt the tree specifically. I would look for the most used trail, back track it for a reasonable distance, and hunt the down wind side of the trail. That way when the wind swirls, it won't bugger up the area surrounding the tree (if that makes sense). IMHO wind direction/swirling and deer approach are two separate factors so I'm only speaking in generalities due to this. I would also look to hunt this particular area in the mornings, hoping to play the morning thermals.