I carry one with me in the early fall hunts, but don't need it for the late winter/spring hunts. I only use it if I KNOW that squirrels are right in front of me, but aren't making a sound or moving. I inhale through the barrel to make a squirrel in distress call. Sometimes works, sometimes not.
The problems is that lot's of times they will just stick their head around the tree to see what all the comotion is about, and they don't really move. It also alerts them to your presence, so if you use one, make sure you're camoflauged up.
I only use mine in times (like right now) where there's so much foliage on the trees that you can miss seeing one. In the late winter when there's no leaves on the trees, the squirrels come down to ground level to eat, and the call isn't required.