Interesting thing about the Powerbelt/Barnes deal.
My first 3 deer I killed were with .45 caliber 275 grain powerbelt aerotip. I watched two bucks run off and die. The other one was a doe that ran behind me, so I didn't see that one. No blood trail needed, but I lucked out in finding the doe, since she didn't run off very far. Neither of them ran very far. I thought I had found THE combo for me. I was impressed and happy.
The next year I shot a doe using the same setup. I don't know whether it was too far of a shot, a bad shot, or what...but the first shot wasn't a kill shot. I thought I had lost it, and began looking at the blood trail, which was very faint. After a while--with help from a dog--I finally found it. I had to shoot it 3 more times for it to die. I was horrified/disappointed by the bad performance.
I didn't know if this was an isolated incident, an error on my part, or what... but I decided to try something different.
Enter the .50 and the Barnes bullets...Knight Ultimate Slam 245 grain spitfires. I shot a buck and it left a good blood trail. I must've left my stand early and probably jumped him, because I found a good sized blood pool where he had laid inside a brushy fenceline. However he had run acroos a big field, leaving a faint blood trail...I actually had to have help with this one. I finally found him a few hours later after searching every bit of the thicket he had run into. I guess he had lost so much blood that he didn't have much of a trail to leave.
I haven't tried the .50 cal powerbelts. I guess they will be next.