I've taken a bunch of deer with my 300 WIN Mag using 168TTSX and they perform well. No big blowup like a typical non-bonded jacketed bullet. Minimal meat damage, but deer rarely make it more than 1 or 2 leaps. Also used 180 Accubonds with great success. I also have a 338 RUM which performs amazingly well with the 210TTSX. Ultimately, the alloy and cavity design of the copper bullets determines the performance. Just need to shoot a few critters and see which one gives you the desired results.