Yep, Why dont you just fill a beercan with powder and set it off in your hand?
Shot a .454 super redhawk at an inside range. 3rd shot and the concussion knocked the light off the ceiling in the bay next to us. 12th shot and the Nikon Monarch pistol scope came apart. That gun is NO FUN to shoot.
I would either go with a .45LC or if you really want a big hammer, get the .480 ruger or the .50cal.
I have a .45LC and can shoot 2" groups at 50yds. Easily pushes a 300gr xtp 1200fps with 2400 powder.