All great guns and calibers mentioned above, but it's really up to you and where you hunt.
If you're an ambidextrous shooter like myself that wants to fill the freezer, you might not op for a bolt gun. I have a Marlin lever gun in .35 Rem with a crisp, aftermarket trigger that's a tack driver. Even with a scope, I like it's balance, and it shows in how I shoot it offhand. Not bragging at all, I'm just saying that I can shoot it a lot better offhand than any other rifle I've shot...ie. bolt guns or my last, a single shot Handi-rifle in .270. However, if you hunt big fields, power lines, or cutovers from a shooting house you'll probably want a more flat shooting rifle. Don't go nuts over firepower, though. Excessive recoil and noise never helped anyone's shooting.