OK. I am the absolute study for this thread. I am 6'6" and 300#. I have shot all kinds of rifles and all kinds of calibers. I chose a Remington 7mm-08 to kill deer from 300yds to 10yds with lots of accuracy. My Mountain DM kicks a little because it only weighs about 6lbs. It's very light even with scope. Some guys on here think you have to kill deer with a 300 Win Mag. You can, but my question is why? .243 are great rounds for eastern whitetails and anything smaller, as well as 7mm-08, and .308. Short actions are great for chambering in my opinion. Even IF you get lucky enough for an elk draw and get a 100 yd or less shot in east TN on an elk, a 7mm-08 will kill it as well.
IF you liked getting the crap kicked out of you, or you might cower down when some good old boy laughs at your "kid's or girl gun", then shoot some huge round, and blow a hole the size of a plate out of a 150# animal. IMO most of those folks can't really shoot, and need to just hit the animal in the ribs and hope for the best. Accuracy is also effected greatly by the anticipated recoil of the rifle, so the less recoil, generally the better accuracy overall. If you like to kill deer dead in their tracks under 300 yards in the east, especially the south, wooded or beanfield, without much thought process to shot dynamics get a 7mm-08 or .308. I chose what I thought was the best combination of both military worlds....7mm bullet on a .308 case.
BTW. I don't think that Remington made that Mountain DM in a .308. I would however love to find the "Classic" made the last year of that series in the .308.
Good luck