I've always kept it simple, with good success.
I fillet my cats. I don't mess with any old school catfish crucifixion methods, and I don't mess with bones.
My favorite breading is a dip in buttermilk, and then a dredge into white cornmeal. No fancy or expensive mixes, or you hide the flavors inherent in the buttermilk, meal, salt and pepper.
One tip on the breading, that I learned from an old KFC employee: press down hard on the fillets to set the breading in solid. Knuckle down hard on it. And if you have a lot of fish, you can set them out on a cookie sheet after you bread them and set them in the freezer. Once solid, you can bag them up for later use. Might even put a little wax paper between the fillets.
Season lightly in the cooking, then add what flavors you want by using dips, sauces, or shakers at the dinner table. I'm betting you'll enjoy the simplicity of just the fish.