I have used them out of my 270 WSM, and my 264 Win Mag, and have had nothing but good luck with them. My 264 is scary accurate with them, and it doesn't seem to care which powder or how fast or slow I push it, it just likes that bullet. I think I have taken 6 critters with the Scirocco between the 2 guns. The total distance anything traveled after the hit is 10 yards of all 6:
1. 270 WSM yote at about 30 yards. DRT
2. 270 WSM doe at about 25 yards. DRT
3,4 270 WSM 2 hogs, 40 yards, both DRT
5,6 264 Win Mag 2 does. 1st doe DRT, 45 yards. 2nd doe 75 yards. Dropped at the shot, somehow got up and tried to run with both shoulders gone. Stumbled 10 yards and fell over dead.
Needless to say that is pretty good results in my book. FWIW the 270 WSM was with Sciroccos, the 264 is Scirocco 2s.