Camping onsite with TWRA guys will give you a hand up in my opinion. You will be onsite without a commute which will encourage you to hunt more, and it will allow you to maximize your time in the woods without the drive time, etc. You will make friends and stay "in the know" as to what all is going on that weekend if you are on the WMA more. You can always drive to local eateries at night if you desire.
For hotels, look to the south across the state line in Southaven, MS. Regardless of the hotel, or location, secure your valuables, stay aware of your surroundings, and be smart about everything.
Best of luck!