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CWD question
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<blockquote data-quote="ADR" data-source="post: 5706086" data-attributes="member: 12473"><p>I'm by far an expect but was educated on this subject through school for my profession. One of the earlier and maybe earliest known infections of prion or prion like disease was found in an aborigine tribe i believe in Africa. A ritual they held was to eat the brains of the deceased tribal members. It was observed that many of the tribe started succumbing to neurological disease. At the time of my education, it was believed that this occurred due to a mutation in a protein that resulted in the beta pleaded sheet protein that is now referred to as a prion.</p><p>That's what a prion is at a simple level is a misguided or malformed protein that results in a beta pleated sheet. So to answer your question, unless the scientific community has changed their stance, simple mutations cause the misfolded protein initially. </p><p>Hope that answers your question.</p></blockquote><p></p>
[QUOTE="ADR, post: 5706086, member: 12473"] I’m by far an expect but was educated on this subject through school for my profession. One of the earlier and maybe earliest known infections of prion or prion like disease was found in an aborigine tribe i believe in Africa. A ritual they held was to eat the brains of the deceased tribal members. It was observed that many of the tribe started succumbing to neurological disease. At the time of my education, it was believed that this occurred due to a mutation in a protein that resulted in the beta pleaded sheet protein that is now referred to as a prion. That’s what a prion is at a simple level is a misguided or malformed protein that results in a beta pleated sheet. So to answer your question, unless the scientific community has changed their stance, simple mutations cause the misfolded protein initially. Hope that answers your question. [/QUOTE]
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