I'm going to be a contrarian on this one. Bucks make sign (rubs and scrapes) as communication devices. That is the signs' purpose. Bucks will only make sign (because it takes a lot of energy to make sign) where they know (by scent) that numerous deer congregate. In essence, they do not make sign equally along their entire travel route. The sign will be concentrated wherever their travels take them through high deer interaction areas. Long stretches of a buck's travels will have no sign at all because they are traveling through areas of low deer activity (outside of themselves). The point being, just because an area displays no sign doesn't mean it is a bad area to hunt.
As I've said many times, if you're after older, hunter-wary bucks:
* Hunt where no one else has been hunting
First, older bucks quickly pick up on areas where they DO NOT encounter much human scent. These are sanctuary areas for them (even if there is no major difference in habitat - the key is a lack of human interaction). Often, these areas develop because hunters find no sign in the area, hence believe it is a bad place to hunt. But if that area contains the right terrain and/or habitat, it could very well be part of an older buck's travel pattern he is specifically using to avoid contact with hunters.
Four of the oldest and best bucks I've ever killed were taken from areas no one had been hunting. And why had no one been hunting there? 1) No sign at all, and 2) the locations were too close to other non-hunting human activity (near a house, near a public road, etc.). If an area has the right combination of terrain, habitat, and lack of hunting pressure, don't ignore it just because there is no sign.