Does anyone have a recommendation for a good hunting load to develop for a .270 Win pistol barrel on an Encore?

This is for my Brother-in-Law. He's been shooting the Rem. Reduced Recoil ammo and it's not working out for him accuracy-wise. He's been giving me his brass so I can neck-size them with my dies, but I've never loaded for a pistol and can imagine that I need a faster burning powder than what I use in my rifle (RL22).

Also what bullets should I consider?