I load my 22-250 with 60 grain Partitions on top of the listed max load of superformance, going back to RL15 for a cleaner burn, 210M primers and R-P brass, in a Browning ABolt. Out to 100 yards, probably further if it was necessary, it'll kill according to the guy pulling the trigger. It is a very accurate round. I know it'll punch through a deer.